MD Complete Wrinkle and Radiance Remedy Reviews – Is It Safe?

MD Complete Wrinkle and Radiance Remedy deliver dermatologist-level improvements against dark spots on the skin. Reveals smoother, more youthful-looking skin.
By - Updated May 18, 2022

What is MD Complete Wrinkle and Radiance Remedy?

MD Complete Wrinkle and Radiance Remedy is a retinol-based serum that claims to reduce fine lines and wrinkles. It is marketed as a potent retinol and vitamin C product that the manufacturer compares to prescription and in-office laser treatments.

MD Complete Wrinkle and Radiance Remedy is part of an anti-aging line that includes eight products that the company claims could reduce fine lines, dark spots, and could moisturize skin. The products are sold through the company’s Web site and at select CVS and Target stores.

Pros and Cons of MD Complete Wrinkle And Radiance Remedy

MD Complete Wrinkle and Radiance Remedy

  • Form:Lotion
  • Skin Type:All Skin Type
  • Benefit:Anti-aging, Melanin Reduction
  • Ingredients:Pure Retinol, Peptides, Vitamin C
  • Brand:MD Complete by Dr. Brian Zelickson
  • Weight:1 Fl. Oz.


  • The pure retinol in this product is less abrasive than tretinoin and may help accelerate skin cell turnover to help firm and plump skin.
  • Peptides may help treat the common signs of aging, such as fine lines and wrinkles.
  • This product may even skin tone and refine the texture of the skin.
  • The fruit seed extract combination could hydrate, moisturize and nourish the skin to help with radiance.


  • The specific amount of the more than 50 ingredients are not known, and the ingredient propylene glycol, which is listed third on the ingredients list, may aid harmful chemicals to enter the skin faster, causing irritation[3].
  • Some individuals may experience red or inflamed skin from the use of cetyl alcohol[4].
  • The use of niacinamide has caused stomach discomfort, nausea and headaches in some individuals[5].
  • This product may not be recommended to be used by women who are pregnant or breastfeeding.

Who is the Manufacturer of MD Complete Wrinkle and Radiance Remedy?

The MD Complete line of skincare products is manufactured by MD Complete, a company started by dermatologist Dr. Brian Zelickson, M.D. The manufacturer can be contacted via email or by telephone, according to its Web site.

The company products two lines of products, one for acne and one for foraging. MD Complete Wrinkle and Radiance Remedy is part of the aging product line.

What are the Ingredients in MD Complete Wrinkle and Radiance Remedy?

The manufacturer states that MD Complete Wrinkle and Radiance Remedy is comprised of more than 50 different ingredients, but some of the key ingredients are listed below:

Pure Retinol: A natural form of Vitamin A that is milder version of tretinoin and may diminish signs of aging and promote collagen production[1].

Peptides: Amino acids that may reduce fine lines and wrinkles and smooth skin texture[2].

Vitamin C: May smooth and brighten skin and reduce signs of aging [6].

Fruit Seed Extracts: A combination of antioxidants, which include cranberry, raspberry, sunflower, and black cumin, which could hydrate, moisturize and nourish the skin [7].

How Does MD Complete Wrinkle and Radiance Remedy Work?

The manufacturer states that MD Complete Wrinkle and Radiance Remedy should be used after cleansing the face. The ingredients in MD Complete Wrinkle and Radiance Remedy, including the pure retinol, peptides, and vitamin C, may help reduce the signs of aging by encouraging new cell growth and removing dead or damaged cells. The combination of fruit seed extracts could moisturize the skin to improve the overall appearance.

Is It Worth Buying MD Complete Wrinkle and Radiance Remedy?

The four key ingredients used in MD Complete Wrinkle and Radiance Remedy have been found to possibly reduce the appearance of fine lines and wrinkles, moisturize skin, and firm and brighten skin. However, there are many other ingredients in this product that could have side effects, such as reddening and irritation.


Que: What is Price of MD Complete Wrinkle and Radiance Remedy?

Ans: The cost of a one-ounce bottle of MD Complete Wrinkle and Radiance Remedy, which the manufacturers claim will last between 60-90 days, costs $39.99.

Que: Who Should Use MD Complete Wrinkle and Radiance Remedy?

Ans: The manufacturer recommends that MD Complete Wrinkle and Radiance Remedy is used by customers who are focused on anti-aging repairs, such as hydrating skin, promoting collagen production, reducing wrinkles, and moisturizing the face.

Que: How to Apply MD Complete Wrinkle and Radiance Remedy?

Ans: After washing one’s face, the company recommends applying two pea-sized pumps of this product to the entire face once a day and then moving up to twice a day thereafter. The manufacturer also recommends not using this product daily at first but instead using it every other day until the skin adjusts to the ingredients within this product.

Que: Does it have Money Back Guarantee?

Ans: Yes, the manufacturer states that products can be returned for a full refund within 90 days of the purchase.

Fina Verdict: MD Complete Wrinkle and Radiance Remedy

MD Complete Wrinkle and Radiance Remedy are comprised of ingredients that have been known to improve one’s skin due to aging. The product uses retinol, which is used in many other products to hydrate skin and is less abrasive than other ingredients.

The price is also comparable to other anti-aging products, although the bottle is only one fluid ounce. However, the manufacturer claims this small amount will last anywhere from 60-90 days.

As people begin to age, they may begin to see changes within their skin, such as wrinkles, fine lines, uneven skin tone, and moisture loss. There are numerous products on the market that claim to improve aging skin. MD Complete Wrinkle and Radiance Remedy may help with these aging issues. However, there may be other products that have fewer ingredients that may not cause any unwanted side effects.

As we age the composition, texture and appearance of our skin changes. Signs of skin aging include wrinkles, fine lines, loss of moisture, uneven tone, and dull, tired-looking skin. There are countless anti-wrinkle creams on the market promising to make skin look and feel younger. Many anti-wrinkle creams promise everything short of a facelift or to provide the much sought after "fountain of youth". In reality most are just moisturizers marketed as anti-aging products.

Below you'll find some of the most effective wrinkle serum formulations on the market today, in our opinion:


Our Top Wrinkle Serum

#1. DRMTLGY Needle-Less Serum

Overall Grade: A+
DRMTLGY Needle-Less Serum Rating Editor Rating Learn More >>
Smoothes Wrinkles*
Improves the Look of Skin Fullness*
Tightens Large Open Pores*
Hydrates the Skin to Give a Radiant Glow*
Promotes a Youthful Appearance*
Ingredient Safety
Projected Effectiveness
Return Policy
Customer Satisfaction
Overall Rating 4.9/5


  • Feels Super Light on Skin
  • 60 Days money-back guarantee
  • Non-greasy formula
  • Has a luminous finish
  • Non-messy opaque liquid
  • Non-messy lotion base
  • Lightweight formula
  • Easy-to-use bottle with dropper
  • Dermatologist recommended
  • Fragrance free formula


  • Different skin types may experience different results

Customer Review & Rating: 4.9/5

"This is the holy grail. I have seen a huge difference in how my skin looks and feels. My crows feet have become minimal in my 60 year young face. I am addicted to all products in this line. They all work and are affordable." - By Liz Melendez


The DRMTLGY Needle-Less Serum is perfect for the people witnessing the fine lines, wrinkles, uneven skin tone & other anti aging problems. The product contains incredible active ingredients, the customer reviews have claimed it worth the price. The serum is lightweight on skin & is clinically proven to reduce the signs of aging.

Check Price >>

#2. Gle Skincare for Wrinkles

Overall Grade: A
Gle Skincare Rating Editor Rating Learn More >>
Improves Stubborn Wrinkles*
Delays Skin Aging*
Improve Skin Elasticity & Firmness*
Reduces Puffiness Around the Eyes*
Hydrates the Under-Eye Area*
Ingredient Safety
Projected Effectiveness
Return Policy
Customer Satisfaction
Overall Rating 4.8/5


  • Dermatologically Tested
  • Hypoallergenic
  • Cruelty-Free
  • Scent-Free Formula
  • Rich in antioxidants
  • Immediate Visible Results
  • Suitable For All SkinTypes
  • Easy-To-Use Handy Bottle
  • pH-balanced
  • Clinically Proven


  • It is only sold online

Customer Review & Rating: 4.8/5

"I OFFICIALLY BELIEVE IN MIRACLES!! I have been using my stuff for only 3 days specifically for the lines that have started forming on my forehead along with some crows feet and my belly where I have stretch marks from pregnancy. I already see a difference!!! The big line on my forehead is invisible almost and I can see a difference on my belly too. I use it in the morning after my shower and at night before I go to bed I highly recommend this product." - By Perla Parramore


Customers say that Gle Skincare for wrinkles is has done magic to their anti aging problems as they have witnessed visible results immediately. The product is specifically formulated with Vitamin Complex, Algae Extract & Jojoba Oil to target the stubborn wrinkles & slow down the further signs of aging. The product also protects skin tone from photo-aging.

Check Price >>

#3. Kollagen Intensiv

Overall Grade: A
Kollagen Intensiv Rating Editor Rating Learn More >>
Diminishes Fine Lines & Crow’s Feet*
Minimizes Dark Circles*
Improve Skin Firmness *
Accelerate Natural Collagen Production*
Prevents Photo-Aging Damage*
Ingredient Safety
Projected Effectiveness
Return Policy
Customer Satisfaction
Overall Rating 4.8/5


  • 60 Day Guarantee
  • Comes in a easy-to-access jar
  • Paraben free
  • Non-greasy
  • Available easily online
  • contains the patented peptide, SYN®-COLL


  • No free trial.

Customer Review & Rating: 4.8/5

"I'm a 32-year old professional actor and dancer. At my age getting jobs as a dancer gets more and more difficult. Because of this, I want to hide my real age as much as possible. That's why I started using Kollagen Intensiv. I'd heard about it before by good reputation, which is why I chose this specific cream. I concur that Kollagen Intensiv is an incredible anti-aging cream that really does work. My skin feels and looks amazing, and I could swear that I appear 10 years younger at least. I am so happy I found this product! It has done amazing things to my skin!- By Delilah


Customers have shared their positive feedback about Kollagen Intensiv that from fine lines and wrinkles to sagginess and even pigmentation problems, each and every one is covered well by this anti wrinkle cream. The product is formulated in such a way that it boosts natural collagen production & hence provides a nourished & hydrated skin all day long.

Check Price >>

Customer Reviews for MD Complete Wrinkle and Radiance Remedy

MD Complete Wrinkle and Radiance Remedy Reviews – Is It Safe?
Reviewer Rating
3.5 / 5.0

Share Your Experience

Leave a Review
Ask Question

Have a Question about ? Please Tell Us What We Are Missing Here!

Note: The Beauty Insiders isn't a healthcare provider. We can't respond to health questions or give you medical advice.
Submit Your Privacy is important to us.

Leave a Reply

Your email address will not be published. Required fields are marked *

75 characters remaining.

Your Rating:05

2000 characters remaining.

Thanks for submitting your comment!

The Beauty Insiders takes every opportunity to use high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial guidelines to learn more about how we keep our content accurate, reliable, and trustworthy.

[6] Chambial S, Dwivedi S, Shukla KK, John PJ, Sharma P. Vitamin C in disease prevention and cure: an overview. Indian J Clin Biochem. 2013;28(4):314-328. doi:10.1007/s12291-013-0375-3