What is Skinmedica Retinol Complex?

Skinmedica Age Defense Retinol Complex is an anti-aging product that utilizes retinol as the key ingredient in correcting and protecting your skin from wrinkles, age spots, and other visible signs of skin aging but causes redness or itching on the skin.

This product is brought to you by Skinmedica, the skincare that became part of Allergan, the multinational pharmaceutical company in 2012.

Skinmedica was established in 1999 by Dr. Richard Fitzpatrick. From then to this day Skinmedica strives to be at the forefront of science and technology when it comes to caring for your skin.

Pros and Cons of Skinmedica Retinol Complex

Skinmedica Retinol Complex

  • Form:Serum
  • Skin Type:All Skin Type
  • Benefit:Enhances Skin Tone, Texture, and Resiliency
  • Ingredients:Retinol, Ceramides, Niacinamide,Peptides
  • Brand:Skinmedica
  • Weight:1 Fl. Oz.


  • Skinmedica Retinol Complex harnesses the power of Vitamin A, proven time and again to have powerful and undeniable age-defying functions that benefit your skin but may cause redness on skin.
  • This product is packaged in an opaque, airtight bottle which helps keep its retinol content and other beneficial ingredients from breaking down.


  • This product is excessively expensive given the composition of the formula and the fact that there are more inexpensive alternatives made with more or less the same ingredients and similar commitments concerning benefits of product use.
  • Skinmedica Retinol Complex reviews indicate that not all users are able to tolerate this formula.
  • There is no money back guarantee on this product.

Skinmedica Retinol Complex – Does It Really Work?

Based on claims made by the manufacturer, this product has been formulated to deliver for you the following benefits:


*All individuals are unique. Your results can and will vary.

  • Deliver mild and gentle exfoliation using retinol at 1.0 per cent concentration.
  • Soothe and calm skin inflammation, relieving your skin of itchiness and redness.
  • Smoothens out your fine lines and wrinkles as it lightens your dark marks.
  • Enhances your skin’s repair and renewal to gradually reveal a blemish-free skin layer with every turnover.
  • Boost your skin’s antioxidant protection and rebuild the protective barrier to help your skin better resist multiple factors that age and damage your skin.

What are the Ingredients in Skinmedica Retinol Complex?

Retinol (1.0%): A Vitamin A derivative that acts on your skin to correct it from imperfections related to aging by facilitating more efficient exfoliation, faster skin regeneration, and more frequent turnovers [2].

Ceramides: Help restore and strengthen your skin’s protective barrier to make it better able to resist multiple factors that cause irreversible damages to your skin matrix and skin cells [3].

Rice Bran Wax: It has moisturizing properties, and it also helps relieve skin inflammation [1].

Niacinamide: It functions as an antioxidant, and it is also capable of lightening dark marks, improving microcirculation, and reviving your skin’s optimal energy levels to reinvigorate your skin. But it might cause itching on redness on the skin [4].

Peptides: Enhance skin repairs and renewal down to the cellular level, making newer, blemish-free skin appear healthier and younger-looking.

How To Apply Skinmedica Retinol Complex?

  • Skinmedica Retinol Complex is recommended for use once up to three times weekly, depending on your skin’s tolerance to this formula. Since this product contains retinol, this product needs to be gradually worked into your skin to help your skin adjust to the formula.
  • Start by using once weekly, slowly increasing frequency up to thrice weekly only.
  • When you notice irritation, cut down on the frequency of use or, stop using the product completely.
  • Use sunscreen during the day, throughout the whole duration of product use, and beyond.

Does Skinmedica Retinol Complex Have Any Side Effects?

Based on the ingredients and reviews, the following side effects may be experienced when using the Skinmedica Age Defense Retinol Complex:


*All individuals are unique. Your results can and will vary.

  • Skin irritation and allergic reactions due to several ingredients, including retinol.
  • Increased risk for neurotoxicity due to phenoxyethanol.
  • Increased risk for diseases associated with the reproductive organs due to EDTA.

Final Verdict: Skinmedica Retinol Complex

Skinmedica Retinol Complex will most definitely bring about improvements to your wrinkles and age spots — any product with Vitamin A at any level of concentration will do so. However, this product is not guaranteed to be suitable for use on all types of skin. Also, there is no money-back guarantee on this product.

Read or Regret Forever! Best Treatment for Deep Wrinkles on Face

As we age the composition, texture and appearance of our skin changes. Signs of skin aging include wrinkles, fine lines, loss of moisture, uneven tone, and dull, tired-looking skin. There are countless anti-wrinkle creams on the market promising to make skin look and feel younger. Many anti-wrinkle creams promise everything short of a facelift or to provide the much sought after "fountain of youth". In reality most are just moisturizers marketed as anti-aging products.

Below you'll find some of the most effective wrinkle serum formulations on the market today, in our opinion.


Our Top Anti Aging Products

#1. Beverly Hills MD Dermal Repair Complex

Overall Grade: A+
Beverly Hills MD Dermal Repair Complex Rating Editor Rating Learn More >>
Reduces Fine Lines and Wrinkles*
Improves Skin Elasticity*
Increases Moisture and Collagen Production*
Reduces the Appearance of Sagging and Drooping*
Improves Strength and Quality of Hair and Nails*
Ingredient Safety
Projected Effectiveness
Return Policy
Customer Satisfaction
Overall Rating 4.9/5


  • 90-day money-back guarantee
  • Good quality ingredients
  • Great for all skin types
  • The product is very budget-friendly
  • Protects skin from UV
  • Cruelty-Free
  • Made in the USA


  • Due to popularity, sometimes it’s on backorder/sold out

Customer Review & Rating: 4.9/5

"After using this product for 1 month I am seeing good results, my skin seems to be a plumber and the skin around my jawline is firming up. I am so far happy with the results and cant wait to see how much more my skin will improve over time." - By Dana Jackson


According to the customer's feedback & reviews, Beverly MD Dermal Repair Complex is successfully tackling the skin problems such as anti-aging, wrinkles, dehydration of skin, and smoothening the skin texture internally and externally by increasing the moisture & collagen production. The key ingredients in the product such as saw palmetto, hydrolyzed collagen, hyaluronic acid & vitamin B hydrate & nourish the skin deeply.

Check Price >>

#2. Dermelect

Overall Grade: A
Dermelect RatingEditor Rating Learn More >>
Improve Skin Elasticity & Firmness*
Reduces Fine Lines and wrinkles*
Reduces Pore Sizes*
Tightens Skin*
Reduces Hyperpigmentation*
Ingredient Safety
Projected Effectiveness
Return Policy
Customer Satisfaction
Overall Rating 4.9/5


  • All natural and professional-quality ingredients
  • Good for all Skin Type
  • Prevents signs of aging.
  • Gluten Free
  • Vegan Free
  • Cruelty Free
  • 30-day money back guarantee


  • Patch test is suggested for dry skin

Customer Review & Rating: 4.8/5

"Great product and it's quickly absorbed. Works wonders. If you want a balanced look to your face this is a must have" - By Chris


According to reviews of Dermelect, this product helped users' skin become more luminous, supple, firm, and pore-less over time. The majority of customers are happy with this product.

Our skin's makeup, texture, and appearance vary with age. Wrinkles, fine lines, moisture loss, an uneven tone, and dull, drained-looking skin are all indications of skin aging.

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