Brio Anti-Wrinkle Day and Night Serum Reviews – Should You Trust This Product?

Brio Anti-Wrinkle Day and Night Serum is a significant breakthrough in anti-aging skincare and helps your skin appear more radiant, healthy.
By - Updated May 19, 2022

What Is Anti-Wrinkle Brio Day And Night Serum?

Brio Skin Serum is manufactured in the United States by Hydra Skin Sciences. It is a vitamin C serum meant to improve the skin’s condition and restore an active low by reducing the appearance of fine lines, wrinkles, and dark circles around the eyes.

The manufacturer offers a trial size. Regular bottles of the product are available. Two bottles of the product are included as there is a day and night version of this serum.

Anti-Wrinkle Brio Day And Night Serum Pros and Cons

Anti-Wrinkle Brio Day and Night Serum Review

  • Form:Lotion
  • Skin Type:All Skin Type
  • Benefit:Provides Firmer, More Youthful Looking Skin, Collagen Production Increases
  • Ingredients:Red Tea Extract, Hyaluronic Acid, Snow Algae Powder, Matrixyl 3000
  • Brand:‎Brio
  • Weight:0.5 oz/14.5 ml


  • The ingredients included in the serum are all-natural. The use of hyaluronic acid as a part of the formula means there are fewer risks for side effects, as HA is naturally found in the body.
  • Brio Skin Serum comes in both day and night formulas, meaning that the manufacturer carefully thought about who would be using the product and how.


  • Though there are benefits associated with the individual components of Brio Skin Serum, there are no clinical studies to back up claims made by this specific product.
  • The ingredients are listed but specific amounts are not mentioned.
  • There are also no studies that explore the differences between the day and nighttime serums in detail.
  • The cost of the product could also be prohibitive for consumers.

What Are The Ingredients In Anti-Wrinkle Brio Day And Night Serum?

Brio Skin Serum lists the following ingredients as a part of its formula:

Red Tea Extract: This ingredient contains many antioxidants known for their benefits to the skin [1].

Hyaluronic Acid: Naturally found in the skin, it’s a natural sugar that strengthens the skin’s barrier and attracts moisture. Namely, some people complain that their skin dries out after using hyaluronic acid [2].

Snow Algae Powder: The algae this powder is derived from grows in extremely cold climates that allow it to develop specific nutritional characteristics that benefit the skin. It assists with skin reparation.

Matrixyl 3000: A combination of two peptides, this ingredient decreases the appearance of crow’s feet, wrinkles, and fine lines. However, the skin feels red [3].

How To Apply Anti-Wrinkle Brio Day And Night Serum?

  • The manufacturer states that 3-5 drops of the serum can be gently massaged in problem areas, such as under the eyes, neck, and anywhere wrinkles or fine lines are present.
  • There is a day and night formula for this serum.


Que: Where To Buy Brio Anti-Wrinkle Day and Night Serum?

Ans: You can buy the product from its official website and online retailers.

You May Also LikeAnti-Aging Sevan Skin Serum

Final Verdict: Brio Anti-Wrinkle Day And Night Serum

Brio Skin Serum has a day and night formula that makes it possible to reap skin benefits at specific times of the day.

The ingredients are all-natural and known for their various benefits, antioxidants, and abundance of nutrients. None of the ingredients listed are known irritants.

Still, some consumers may want to know specific amounts of ingredients used. It would also help to see factual clinical trials that back the claims of the product.

Though the product seems to do what it says, consumers should also be aware of other options that do the same or similar things for a reduced cost. Check out other options like NIOD Multi-Molecular Hyaluronic Complex Reviews and Pure Radiance Restore Reviews that offers similar benefits to this serum.

As we age the composition, texture and appearance of our skin changes. Signs of skin aging include wrinkles, fine lines, loss of moisture, uneven tone, and dull, tired-looking skin. There are countless anti-wrinkle creams on the market promising to make skin look and feel younger. Many anti-wrinkle creams promise everything short of a facelift or to provide the much sought after "fountain of youth". In reality most are just moisturizers marketed as anti-aging products.

Below you'll find some of the most effective wrinkle serum formulations on the market today, in our opinion:


Our Top Wrinkle Serum

#1. DRMTLGY Needle-Less Serum

Overall Grade: A+
DRMTLGY Needle-Less Serum Rating Editor Rating Learn More >>
Smoothes Wrinkles*
Improves the Look of Skin Fullness*
Tightens Large Open Pores*
Hydrates the Skin to Give a Radiant Glow*
Promotes a Youthful Appearance*
Ingredient Safety
Projected Effectiveness
Return Policy
Customer Satisfaction
Overall Rating 4.9/5


  • Feels Super Light on Skin
  • 60 Days money-back guarantee
  • Non-greasy formula
  • Has a luminous finish
  • Non-messy opaque liquid
  • Non-messy lotion base
  • Lightweight formula
  • Easy-to-use bottle with dropper
  • Dermatologist recommended
  • Fragrance free formula


  • Different skin types may experience different results

Customer Review & Rating: 4.9/5

"This is the holy grail. I have seen a huge difference in how my skin looks and feels. My crows feet have become minimal in my 60 year young face. I am addicted to all products in this line. They all work and are affordable." - By Liz Melendez


The DRMTLGY Needle-Less Serum is perfect for the people witnessing the fine lines, wrinkles, uneven skin tone & other anti aging problems. The product contains incredible active ingredients, the customer reviews have claimed it worth the price. The serum is lightweight on skin & is clinically proven to reduce the signs of aging.

Check Price >>

#2. Gle Skincare for Wrinkles

Overall Grade: A
Gle Skincare Rating Editor Rating Learn More >>
Improves Stubborn Wrinkles*
Delays Skin Aging*
Improve Skin Elasticity & Firmness*
Reduces Puffiness Around the Eyes*
Hydrates the Under-Eye Area*
Ingredient Safety
Projected Effectiveness
Return Policy
Customer Satisfaction
Overall Rating 4.8/5


  • Dermatologically Tested
  • Hypoallergenic
  • Cruelty-Free
  • Scent-Free Formula
  • Rich in antioxidants
  • Immediate Visible Results
  • Suitable For All SkinTypes
  • Easy-To-Use Handy Bottle
  • pH-balanced
  • Clinically Proven


  • It is only sold online

Customer Review & Rating: 4.8/5

"I OFFICIALLY BELIEVE IN MIRACLES!! I have been using my stuff for only 3 days specifically for the lines that have started forming on my forehead along with some crows feet and my belly where I have stretch marks from pregnancy. I already see a difference!!! The big line on my forehead is invisible almost and I can see a difference on my belly too. I use it in the morning after my shower and at night before I go to bed I highly recommend this product." - By Perla Parramore


Customers say that Gle Skincare for wrinkles is has done magic to their anti aging problems as they have witnessed visible results immediately. The product is specifically formulated with Vitamin Complex, Algae Extract & Jojoba Oil to target the stubborn wrinkles & slow down the further signs of aging. The product also protects skin tone from photo-aging.

Check Price >>

#3. Kollagen Intensiv

Overall Grade: A
Kollagen Intensiv Rating Editor Rating Learn More >>
Diminishes Fine Lines & Crow’s Feet*
Minimizes Dark Circles*
Improve Skin Firmness *
Accelerate Natural Collagen Production*
Prevents Photo-Aging Damage*
Ingredient Safety
Projected Effectiveness
Return Policy
Customer Satisfaction
Overall Rating 4.8/5


  • 60 Day Guarantee
  • Comes in a easy-to-access jar
  • Paraben free
  • Non-greasy
  • Available easily online
  • contains the patented peptide, SYN®-COLL


  • No free trial.

Customer Review & Rating: 4.8/5

"I'm a 32-year old professional actor and dancer. At my age getting jobs as a dancer gets more and more difficult. Because of this, I want to hide my real age as much as possible. That's why I started using Kollagen Intensiv. I'd heard about it before by good reputation, which is why I chose this specific cream. I concur that Kollagen Intensiv is an incredible anti-aging cream that really does work. My skin feels and looks amazing, and I could swear that I appear 10 years younger at least. I am so happy I found this product! It has done amazing things to my skin!- By Delilah


Customers have shared their positive feedback about Kollagen Intensiv that from fine lines and wrinkles to sagginess and even pigmentation problems, each and every one is covered well by this anti wrinkle cream. The product is formulated in such a way that it boosts natural collagen production & hence provides a nourished & hydrated skin all day long.

Check Price >>

Customer Reviews for Anti-Wrinkle Brio Day and Night Serum

Brio Anti-Wrinkle Day and Night Serum Reviews – Should You Trust This Product?
Reviewer Rating
2.8 / 5.0

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  1. Carla Conti

    Your Rating:

    Would not buy again
    I used this for six weeks and didn’t see any of the results I was hoping for, mainly firming and smoothing. It didn’t irritate my skin, which is great, but it also didn’t seem to do anything. I did not find it to be drying, as some do, but it did feel like it sat on my skin as opposed to absorbing it. Oh well, on to the next product!

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The Beauty Insiders takes every opportunity to use high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial guidelines to learn more about how we keep our content accurate, reliable, and trustworthy.

[1] Khan, Naghma, and Hasan Mukhtar. “Tea and health: studies in humans.” Current pharmaceutical design vol. 19,34 (2013): 6141-7. doi:10.2174/1381612811319340008.
[3] Aldag C, Nogueira Teixeira D, Leventhal PS. Skin rejuvenation using cosmetic products containing growth factors, cytokines, and matrices: a review of the literature. Clin Cosmet Investig Dermatol. 2016;9:411-419. Published 2016 Nov 9. doi:10.2147/CCID.S116158