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9 Best Menopause Supplements 2022

Popular supplements That help balance the hormonal changes that occur during perimenopause

Last Updated: May 20, 2022

Best Menopause Supplements 2018 - Shutterstock Image

Whoopi Goldberg once said about menopause: “All of a sudden I don’t mind saying to people, ‘You know what? Get out of my life. You’re not right for me. ’ It’s wonderful and liberating. ” Her positive perception of menopause, however, is not a shared perception with every other woman around the world who is going through this late reproductive phase in their life.

Is It All In The Mind?

Partly, yes, the symptoms of menopause are influenced by what’s going on in your head as well as your state of happiness but, the physiological changes[1] happening around the time menopause sets in are real and undeniable. Before you even start your hunt for the best menopause supplements, it will help if you take a closer look at what could be happening to your body that’s making you feel queasy, and likely irritable as well.

Estrogen is the one hormone that defines so much happening to your body and mind around menopause. When its level significantly drops, you can expect the following symptoms of menopause to set in:

  • Vaginal dryness.
  • Night sweats.
  • Hot flashes.
  • Difficulty of focusing.
  • Marked lonelier state of mind.
  • Anxiety and Depression
  • Mood swings and frequent irritability.
  • Difficulty sleeping.
  • Restless legs syndrome.
  • High blood pressure and frequent palpitations.
  • Migraine.

Both the common menopause symptoms as well as their longer-term effects are accompanied by a generally compromised body functioning that is more particularly defined by the physiological changes, mostly driven by the dwindling supply of estrogen, some of which are identified below:

  • Lack of libido.
  • Lower levels of endorphins produced.
  • Slower metabolism.
  • Compromised bone growth and development.
  • Halting of menstruation.
  • Increased levels of cortisol in the body causing stressful reactions.

Is There Help Available?

Yes, and you shouldn’t hesitate to seek help from products, procedures, and other people to help you create your menopausal regimen to which your body will be responsive. You must note though that subscribing to treatments for menopausal symptoms is far from being a rocket science. For the most part, treatment requires a phase of trial and error before you finally find the regimen, and possibly a menopausal relief supplement that suits you well.

It is rather unfortunate that science and technology concerning menopause were slow to progress relative to the advanced treatments of many other health conditions and diseases. At one point, Hormone Replacement Therapy (HRT)[2] became the most trusted and, at that time, the most effective way that women could deal with the sometimes painful and sometimes embarrassing symptoms related to menopause. HRT became the salvation menopausal women turned to as soon as they started to encounter problems during menopause.

However, after the Women’s Health Initiative (WHI) released the results of a 15-year study that showed HRT increased the risks of women who undergo HRT to breast cancer and heart diseases, it didn’t take long before the spotlight left HRT. Presently, HRT is now only being prescribed for those who stand to benefit more relative to the risks associated with the treatment. Women and medical practitioners, alike, have since turned to supplementation for answers.

The Top Rated Menopause Supplements:

Based on the analytical review of evidence available on botanical and dietary supplements (BDS)[3] published in 2005 in the Journal of Women’s Health, even medical practitioners and nurses are poorly informed about BDS and Menopause supplements.

See below to be guided on how to choose menopause supplements:

  • Keep in mind that there are generally 2 types of supplements for menopause — those which are laden with hormones to make up for your dwindling estrogen and progesterone levels, and those which are formulated with botanical ingredients, many of which have been used for centuries for the relief of symptoms associated with menopause and perimenopause.
  • Check available third-party evidence to establish the reliability of claims being made by any manufacturer usually regarding a primary botanical ingredient used as menopause supplement ingredients. According to the same BDS study mentioned above, the researcher wrote that black cohosh appears to be the most effective botanical for the relief of bad mood, hot flashes, and night sweats, while St. John’s Wort has been shown to relieve mood swings.
  • Look for clinical evidence of product efficacy. The best supplements for menopause will invest in R & D and will be more than willing to present the results of these types of studies.

Since there are shelves after shelves of menopause supplements available in the market, we’ve rounded up 10 menopause relief supplements that are worth your time, effort, and resources to go check out and probably even resolve to try.

Here are your 9 best supplements for menopause:

#1: Amberen

Amberen Multi Symptom Menopause relief

Amberen Multi Symptom Menopause relief

This supplement works by restoring your optimal hormone levels and balance these out while simultaneously improving metabolism rates as well as key nutrients which includes calcium, magnesium and zinc. Its one of the better supplements for night sweats and boosts your antioxidant levels at the same time.

#2: i Cool

I-Cool menopause dietary supplement

I-Cool menopause dietary supplement

This supplement contains one of the best vitamins for menopause symptoms, that is, Vitamin E, which helps you maintain your youthful looks as well as optimal immune response. More importantly, it contains Omega-3, placing a premium on your heart health and making it one of the best perimenopause supplements when blood pressure and palpitations can become frequent and highly unpredictable. Still packed with more, I Cool is also infused with genocide-genistein, a proprietary ingredient that has been clinically proven to relieve hot flashes.

#3: Estrovera

Estrovera Metagenics

Estrovera Metagenics

This is one of the supplements for hot flashes. The primary ingredient is Rhapontic Rhubarb formulated into the proprietary ingredient, ERr731 which has been clinically demonstrated to deliver results that mimic the results of low-dose hormone therapies. The manufacturer further claims that this supplement has been clinically proven to address other menopausal symptoms, including difficulty sleeping, mood swings, fatigue, and vaginal dryness. It can also be considered as one of several supplements for menopause joint pain.

#4: Macafem

With a key ingredient derived from the maca plant indigenous to Peru, this is one of several menopause weight loss supplements that help women keep their healthy weight throughout menopause despite the onset of a slower rate of metabolism. In addition, there are also available studies establishing the positive results of maca in relieving depression, mood swings, sex drive, and energy, and countering other adverse effects associated with menopause.

#5: Remifenin

Remifemin Menopause Supplements

Remifemin Menopause Supplements

Solely relies on the properties of black cohosh to deliver its menopausal relief. Nevertheless, it is one of the most highly regarded botanical supplements for menopause.

#6: Estro500

Estro500 supplement

Estro500 supplement

This is a supplement that works by replacing your hormones, providing you with external sources of estriol and estradiol in a ratio of 8:2. It is one of the supplements for menopause mood swings but also works well in relieving night sweats, hot flashes, and fatigue.

Related: Why Do Women Experience Menopause?

#7: Relizen

Relizen for Menopause

Relizen for Menopause

Also deserving special mention in this list of 9 best menopause supplements, this product is infused with the Swedish Flower pollen extract. It provides you with an all-natural, non-estrogenic way of relieving menopausal symptoms with over 15 years of presence in European markets.

#8: Profemin

Menozac Natural Menopause Support

Menozac Natural Menopause Support

Also made of botanical ingredients, this product improves your mood and helps you better resist anxiety and depression. Key ingredients include Angelica Gigas, Phlomis Umbrosa and Cyanchum Wilfordii.

#9: Menozac

Best Menopause Supplements: Menozac

Menozac Natural Menopause Support

This supplement is formulated with soy seed, black cohosh, and damiana which, combined, deliver multiple functions for the relief of various symptoms associated with menopause.


Que: Do Menopause Supplements really work?

Ans: Menopause Supplements will only help improve the menopause symptoms caused by dietary imbalance, and won’t help improve any symptoms caused by hormonal changes.

Que: Are Menopause Supplements Safe?

Ans: Yes, it is safe and effective for reducing menopausal symptoms.

Que: Is weight gain a side effect of Menopause?

Ans: No, it is not directly associated with weight gain, it may be related to changes in body composition and fat distribution.

Que: Do vitamins help Menopause Symptoms?

Ans: Vitamins B-6 and B-12 may help support cognitive function, which means the ability to think, reason, and remember.


It may seem simple but, these botanical and dietary supplements are generally not very well understood. What makes BDS even trickier that these are not regulated by the US Food and Drug Administration (FDA)[4]
. There are no guarantees so choose well.

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